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Phentermine is a medication commonly used as an appetite suppressant for the short-term treatment of obesity. The drug combines diet, exercise, and lifestyle changes to achieve significant weight loss. Phentermine stimulates the production of neurotransmitters in the brain, which leads to a decrease in appetite and an increase in energy.

Mechanism of action

Phentermine is an anorexigenic drug from the group of amphetamines and phenethylamines. It acts on the central nervous system by stimulating the production of norepinephrine, dopamine, and serotonin, which decreases feelings of hunger and increases energy. This helps to reduce caloric intake and maintain an active lifestyle.

Dosage and use

Phentermine is usually prescribed for a short period, usually no more than 12 weeks. The dosage depends on the patient’s needs and can range from 15 mg to 37.5 mg daily. It is important to follow the doctor’s recommendations and not exceed the prescribed dose. Phentermine is usually taken in the morning before meals or 1-2 hours after breakfast.

Side effects and cautions

Phentermine may cause side effects such as high blood pressure, palpitations, insomnia, irritability, dry mouth, and constipation. Serious side effects such as pulmonary hypertension and heart problems may occur in rare cases. You should see your doctor immediately if you experience any side effects or allergic reactions.

Alternatives to phentermine

If phentermine is not right for you or causes unpleasant side effects, you should talk to your doctor about alternative treatments for obesity. Here are some of them:

  • Orlistat: This drug blocks fat absorption and helps you lose weight. Orlistat is available with or without a prescription.
  • Lorcaserin: This drug acts on serotonin receptors in the brain to help reduce appetite and increase satiety.
  • Semaglutide Pharmacotherapy: Semaglutide is a hormone that helps lower blood sugar levels and decreases appetite. It can be used to treat obesity and type 2 diabetes.
  • Bariatric surgery: If you suffer from obesity and traditional treatments are ineffective, surgery such as gastric bypass or gastric bypass may be recommended.
  • Comprehensive weight loss programs: Under the guidance of nutritionists and physical activity coaches, an individualized weight loss program, including diet, exercise, and psychological support, can be developed.

It is important to remember that obesity treatment must be supervised by a physician and tailored to the patient’s needs. Quick fixes and self-treatment can be dangerous and lead to long-term health problems.

Warnings and precautions when using phentermine

Before you begin taking phentermine, it is important to be aware of possible warnings and precautions to ensure the safety and effectiveness of treatment.

  • Contraindications: Phentermine is contraindicated in certain diseases and conditions, such as arterial hypertension, cardiovascular disease, hyperthyroidism, glaucoma, and allergy to sympathomimetics.
  • Interaction with other drugs: Phentermine may interact with certain medications such as antidepressants, MAO inhibitors, insulin, and other diabetes medications. Make sure your doctor knows about all the medicines you are taking before prescribing phentermine.
  • Pregnancy and breast-feeding: Phentermine is not recommended for use during pregnancy and breastfeeding because its safety for babies has not been studied.
  • Alcohol and drugs: Refrain from drinking alcohol and drugs during the treatment with phentermine, as this may increase the side effects and worsen the treatment results.
  • Overdose: In case of phentermine overdose, you should immediately consult a doctor or call an ambulance. Overdose symptoms may include headache, dizziness, vomiting, rapid heart rate, and seizures.
  • Discontinuing treatment: Do not stop treatment with phentermine without consulting your doctor, as this may cause withdrawal symptoms such as depression and fatigue. Your doctor may gradually reduce the dosage to avoid these symptoms.

By following warnings and precautions, you can provide safe and effective treatment for obesity with phentermine. In addition to using phentermine, following a healthy diet and regular exercise is important to achieve optimal results and maintain a healthy lifestyle.


Phentermine is an effective treatment for obesity and maintaining a healthy lifestyle. However, to ensure the safety and success of the treatment, it is important to strictly follow the doctor’s recommendations, pay attention to warnings and precautions, and lead an active and healthy lifestyle.